“Persistent SARS-CoV-2 Infection with Accumulation of Mutations in a Patient with Poorly Controlled HIV Infection” Ī 22-year-old female with uncontrolled advanced HIV infection was persistently infected with SARS-CoV-2 beta variant for 9 months, the virus accumulating >20 additional mutations. So its hard to explain how it appeared in S Africa.īTW steve this is the issue with the not natural suggestion that some are seemingly pushing – But it is is highly mutated relative to the strains around then. There have been billions of omicron infections so far.

With Omicron we get worse #1 (high ACE2 in the bronchi and above them in the URT), less severe #2, and we have no direct data on #3, but logic says it is worse, for the same reasons #1 is worse.”Īnything’s possible I guess, but this seems unlikely at this stage. They also die from #3, and will be dying of it in very large numbers in the future, but that does not enter the official statistics and thus can be ignored politically. The systemic infection that damages hearts, kidneys, beta cells in the pancreas, endothelial cells, the brain (though perhaps not directly), etc. The hyperinflammatory reaction in the alveoli that causes ARDSģ. “The problem for all of us is that COVID is really three diseases at once:Ģ. Remdesivir – likely minimal if any benefit. With low risk and then getting some natural immunity I just think a catastrophic outcome is less likely there – my gut, not advice of any kind to anyone. Unlikely, but yeh no coming back from that one. It is a sense like when they tested the first nuclear bombs and weren’t completely sure when the chain reaction would stop. deliberately not having a long term control cohort, etc. If likelihoods are really low for both then on the consequence side I just think it is bigger when dealing in new vaccines without the normal clinical trials processes – as shown by detailed critical analysis of the Pfizer trials eg. Presumably we have evolved with some corona virus iterations in the past vs our vaccine tech. Otherwise, if we are dealing in unknowns then I think you need to go with your gut. $File/covid_19_australia_epidemiology_report_56_reporting_period_ending_5_december_2021.pdf RE: cohorts I thought this was harder to find than it should be: Or if otherwise at high risk.Īnyway faced with a looming NHS staffing crisis, the UK government just blinked. There should be a point on a graph where the lines cross.

This paradox suggests a blanket policy is wrong. Paradoxically, the vaccines seem to cause more problems in the young. They confer reasonable protection against serious illness – but at a price.Ĭovid is overwhelmingly more serious for the elderly. They don’t stop infection – and may in fact increase infection. It’s been clear for 12 months that the vaccine is about protecting yourself – or not protecting yourself. Why do these documents have to be leaked? Why can’t there be transparency. Ministers have been issued with a stark warning over mandatory Covid vaccines for NHS workers in England, with a leaked document saying growing evidence on the Omicron variant casts doubts over the new law’s “rationality” and “proportionality”. The economic calendar starts the week with some big releases, namely Euro wide flash 4Q GDP results, then German inflation for January, followed by the Chicago PMI print. Japanese markets are also coming back with the Nikkei 225 closing 1.3% higher at 27076 points while the USDJPY pair is trying to get back on track after quickly reversing on Friday night to the low 115 level but is still finding a lot of overhead resistance here:Īustralian stocks however are pushing lower, having lost confidence over the weekend with the ASX200 closing 0.2% lower to remain below the 7000 point level at 6971 points, while the Australian dollar is still dicing with the key 70 handle, as the USD proves too strong, finding some support on the open here just above:Įurostoxx and Wall Street futures are slowly lifting going into the London open, with the S&P500 four hourly chart showing price ready to take out the absolute key overhead resistance area at the 4430 level that needs to be cleared before calling this a proper bottom or price again heads back to the September 2021 lows at the 4250 level: Mainland Chinese shares are closed for Chinese New Year and won’t be back until next week, but the Hang Seng Index was open for today, currently up a little more than 1% to take back its Friday losses.

Annum per annum arvo part pdf viewer